{"id":1152,"date":"2025-10-23T21:54:46","date_gmt":"2025-10-23T19:54:46","guid":{"rendered":"https:\/\/emanuelabottanilab.it\/team\/giulia-pedrotti\/"},"modified":"2025-11-05T12:27:15","modified_gmt":"2025-11-05T11:27:15","slug":"giulia-pedrotti","status":"publish","type":"team","link":"https:\/\/emanuelabottanilab.it\/en\/team-member\/giulia-pedrotti\/","title":{"rendered":"Giulia Pedrotti, Ph.D."},"featured_media":1153,"parent":0,"template":"","meta":{"_gspb_post_css":""},"class_list":["post-1152","team","type-team","status-publish","has-post-thumbnail","hentry"],"blocksy_meta":[],"yoast_head":"\nGiulia Pedrotti, Ph.D. - Emanuela Bottani Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/emanuelabottanilab.it\/en\/team-member\/giulia-pedrotti\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Giulia Pedrotti, Ph.D. - 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After graduation, she began working on mitochondrial biology, using murine brain organoids to investigate the role of thyroid hormone in regulating mitochondrial metabolism during neurodevelopment.<\/span><span data-ccp-props=\"{"134233117":true,"134233118":true,"201341983":0,"335551550":6,"335551620":6,"335559731":0,"335559739":160,"335559740":240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">She completed her <em>PhD in Neuroscience<\/em> in 2025 at the University of Verona, participating in the European project CureMILS. Her doctoral research focused on evaluating PDE5 inhibitors as reference drugs for Leigh Syndrome, investigating their ability to normalize mitochondrial membrane potential (MMP) defects in neuroprogenitor cells carrying different ATP6 gene mutations, and elucidating their mechanisms of action on MMP and mitochondrial biogenesis.<\/span><span data-ccp-props=\"{"134233117":true,"134233118":true,"201341983":0,"335551550":6,"335551620":6,"335559731":0,"335559739":160,"335559740":240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Since 2025, Giulia has been a <em>Silverstein Fellow<\/em> at the<em> Institute of Biomedicine at Eurac Research<\/em> (Bolzano), where she is investigating how GBA1 mutations disrupt cellular lipid homeostasis in Parkinson\u2019s disease, with a specific emphasis on mitochondrial lipid alterations affecting cellular energy metabolism.<\/span><span data-ccp-props=\"{"134233117":true,"134233118":true,"201341983":0,"335551550":6,"335551620":6,"335559731":0,"335559739":160,"335559740":240}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Recognized for her curiosity, intelligence, and dedication, Giulia approaches research with both rigor and creativity. 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